ea0086oc1.4 | Bone and Calcium | SFEBES2022
Jenkinson Carl
, Desai Reena
, McLeod Malcolm
, Wolf Mueller Jonathan
, Hewison Martin
, Handelsman David
Recent in-vitro studies have shown that vitamin D metabolites undergo conjugation reactions by sulfation and glucuronidation and may be important mechanisms for the inactivation, storage and excretion of analytes. However the circulating concentrations and clinical significance of phase II vitamin D conjugation is unclear as current analysis has almost exclusively been restricted to measuring their unconjugated metabolite forms. In this study we aimed to develop an analytical ...